Recombinant human LH supplementation during GnRH antagonist administration in IVF/ICSI cycles: a prospective randomized study
نویسندگان
چکیده
منابع مشابه
Anovulatory Patients Demonstrate a Sharp Decline in LH Levels upon GnRH Antagonist Administration during IVF Cycles
To evaluate the decrease in luteinizing hormone (LH) levels following gonadotropin-releasing hormone (GnRH) antagonist administration in in vitro fertilization (IVF) cycles, data were retrospectively collected from 305 consecutive IVF or intracytoplasmic sperm injection (ICSI) cycles of patients who underwent ovarian stimulation with gonadotropins and were treated with GnRH antagonist for the p...
متن کاملGnRH agonist versus GnRH antagonist in oocyte donation cycles: a prospective randomized study.
BACKGROUND The specific role of LH in folliculogenesis and oocyte maturation is unclear. GnRH antagonists, when administered in the late follicular phase, induce a sharp decrease in serum LH which may be detrimental for IVF outcome. This study was performed to evaluate whether the replacement of GnRH agonist (triptorelin) by a GnRH antagonist (ganirelix; NV Organon) in oocyte donation cycles ha...
متن کاملRecombinant LH supplementation during IVF cycles with a GnRH-antagonist in estimated poor responders: A cross-matched pilot investigation of the optimal daily dose and timing
Although it is widely accepted that patients, who are considered poor responders to in vitro fertilization (IVF) benefit from recombinant luteinizing hormone (rLH) supplementation during an in vitro fertilization cycle, particularly when gonadotropin‑releasing hormone (GnRH)‑antagonist (ant) treatment is used the optimal administration timing and daily dose of rLH remains to be elucidated. The ...
متن کاملLH Supplementation for Low LH Levels during Antagonist IVF Cycles Improves Live Birth Rates
Introduction: Gonadotropin releasing hormone (GnRH) antagonist IVF protocols often induce a significant decrease in serum luteinizing hormone (LH) levels that may affect assisted reproductive technology cycle outcomes. However, supplementing all women undergoing antagonist cycles with recombinant LH does not improve clinical outcomes. The aim of this study was to assess the impact of LH supplem...
متن کاملReply: Comment on 'Recombinant LH supplementation to a standard GnRH antagonist protocol in women of 35 years or older undergoing IVF/ICSI: a randomized controlled multicentre study'.
bulk of the existing data regarding the use of luteal estradiol priming. Given our use of observational data we made every effort to minimize the faults of the individual studies included in our manuscript, using rigorous methodology and the random effects model to minimize the inter-study differences and improve the applicability of our results to all populations of poor responders across the ...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2004
ISSN: 1460-2350
DOI: 10.1093/humrep/deh369